Mainstream psychiatry maintains that "schizophrenia" is a brain disease, citing research that indicates that the brains of people with psychosis are different from the brains of "normal" people. However research shows that the brain interacts with, and is changed by social experiences. We now know that antipsychotic medications can change brain structures as well.

Brian Koehler, editor of the Neurobiology pages, has discussed the significant overlap between the neuroscience of psychosis and the neuroscience of stress

See Neurobiology page.